Funded Projects – Ongoing & Implemented at Schieffelin Institute of Health Research & Leprosy Center, Karigiri

ONGOING-2011

Projects Funding Agency Investigators Duration
Explainable Artificial Intelligence framework using deep learning neural network and machine learning algorithms for epidemiological prediction and analysis of Leprosy transmission and drug resistance. Indian Council of Medical Research (ICMR). Sathish Kumar Paul, Ilse Horo, S.Jenicka. VIT University, Ebenezer Juliet, VIT University. 2024 – 2028
Interface to fabricate customized insole with dynamic peak plantar pressure data. American Leprosy Missions. Sathish Kumar Paul, Suresh Kumar Sampath, Anupriya, Priscilla Sherin 2023-2025
Investigating a point-of-care and field-friendly Realtime PCR platform to detect subclinical infection among household contacts of leprosy cases. – BIOMEME Platform American Leprosy Missions. Madhusmita Das 2021-2022
Universal cloud Based Platform to Monitor and Prevent Disability in People affected by Leprosy American Leprosy Missions. Sathish Kumar Paul, Suresh Kumar Sampath, Ganga.T 2021-Ongoing
Tactile Sensory Feedback System to Predict and Prevent Peak Plantar Pressures American Leprosy Missions, 4384 Sathish Kumar Paul, Anu Priya 2019-Ongoing
Design Customized Offloading Devices to Promote Healing of Plantar Ulcers Leprosy Research Initiative, 706.18.29/LRI David Prakash Kumar, Sathish Kumar Paul, Jerry Joshua 2017-2020
To identify Mycobacterium leprae associated transcriptomic signatures and host immune signatures that aid as early signals for determination of reaction states in leprosy.

Leprosy Research Initiative, 704.16.57/LRI Madhusmita Das 2016-2020
Mobile Technology (M-Health) – A novel approach to facilitate and motivate self-care among the leprosy affected Leprosy Research Initiative, 705.17.41/LRI/DEF Sathish Kumar Paul, David Prakash Kumar, Richard Joseph, Jerry Joshua 2017-2020
To Investigate the whole Transcriptome and Genomic profile of Drug resistant strains of Mycobacterium Leprae in order to identify Molecular Signatures that aid in the Determination of Drug Resistance in Leprosy ICMR funded Project, F/No: ECD/ ADhoc/Leprosy/ 2014-2674/ FY – 14-15/22/ Karigiri/ NGO Madhusmita Das 2014-2020
Multi centric trial to study the effect of early mobilization as compared to three weeks immobilization following tendon procedure for claw hand ICMR funded Project, No.ECD/TF/Lep/FY-14-15/24/Agra/Govt.15 Jerry Joshua 2014-2020
Effects of the Impact of Counselling Intervention on life situation of the stigmatized vitiligo and Psoriasis Patients ICMR funded Project, No: 5/11/13/10-SAR Valsa Augustuine, Premkumar, Priya Joseph, Richard Joseph 2011-2014
Identifying and reducing the gap between medical and social definition of “Cure” through appropriate methods ICSSR 2011-2013

2010-2000

Projects Funding Agency Investigators Duration
Empowerment of Persons Living with Stigmatizing Conditions Danish Mission Council Development Department 2009-2010
Empower Project Danish Mission Council Development Department 2008-2010
GFATM – IEC (Adivasi project).

Leprosy Research Initiative, 704.16.57/LRI 2008
Prevention and control of Diabetes Mellitus in the Rural and Semi Urban parts of India through a Established Network of Hospitals World Diabetes Foundation 2007-2008
Community Prevention of Impairment & Disability American Leprosy Missions 2007-2009
CBM – Hearing Aids project CBM 2006-2008
Initiative for diagnosis and epidemiological assays for leprosy IDEAL Project 2006-2008
Screening for the Drug Resistance M.leprae using Mouse Foot Pad in Relapse of MB Leprosy. Indian Council of Medical Research (ICMR) 2006-2007
Study of Factors Promoting Active Ageing in a Rural Community. No: 54/1/GER/02-NCD-11 2006-2007
Transient Nasal Carriage of M. Leprae in a Leprosy Endemic Population 2005-2006
Reaching (Women’s Health) the Women American Leprosy Missions 2005-2006
TANSACS – Tamil Nadu state Aids control society. (Integrated counselling and testing ICTC centre) 2005
Training & Evaluating of Knowledge and Skills of Medical Officers in Primary Health Centres in Diagnosis and Management of leprosy DANLEP 2003
Social Assessment of the Rural and Urban poor in Tamil Nadu DANIDA 2003
Neonatal Mortality Surveillance ( Verbal and Social Autopsy), National Health Research initiative , Clinical Epidemiology Unit , Govt. Medical Collage , Nagpur 2003
Enhancing leprosy awareness through community based health education 2002-2003
Leprosy , Disability and Poverty , Development of Strategies in Integrated Leprosy affected Persons with Disabilities in to Rural Poverty Alleviation Programmes Council of Advancement of People’s Action and Rural Technology , GOI , India 2002
Study of Leprosy Beggars : An investigation of leprosy affected beggars as hidden reservoir for transmission of leprosy Indian Council of Medical Research (ICMR) 2002
Activity Limitation study in Leprosy The Leprosy Mission International 2002
Validation of Indicators for CBR programs 2002
Participation Restriction Scale Development The Leprosy Mission International 2002
Reproduction and Child Health program among Leprosy Affected Families 2001
Lactoferrin and Antibodies to Lactoferrin in tears of Leprosy patients Indian Council of Medical Research (ICMR) 2000-2003
INDO – US project entitled “Epidemiological and immunological studies on early events associated with infection of Mycobacterium Leprae 2000-2003
Adolescent Health Project 2000

1999-1990

Projects Funding Agency Investigators Duration
Viability of M.leprae in Lepromatous Patients after Completion 12 and 24 months MDT Indian Council of Medical Research (ICMR) 1999-2002
Care After Cure Project 2 : A Project on Assesment and Care of Leprosy patients released from control in Chitoor District , AP Leprosy Research Initiative, 706.18.29/LRI 1998-2000
Multi-Centric field trials in Single Lesion PB leprosy

Baptist Union of Sweden. 1995 -1997
Disability Prevention & Limitation Program in Leprosy (The “DISLEP” Project) World Health Organisation (WHO) 1995
Multi centric field trials of Ofloxacin containing combined drug regimen in PB leprosy IMPACT (UK) Foundation 1992 – 1999
Multicentric study on Longitudinal Study of Ocular Leprosy World Health Organisation (WHO) 1991-2002

1989-1985

Projects Funding Agency Investigators Duration
Chemoprophylaxis Using Rifampicin Institutional Funding K. Jesudasan, M. Christian, V.K. Pannikar, N. Manimozhi 1987-1994
Histopathological Study of Ocular Tissues from Surgical Procedures in the Hospital N. Suryawanshi (Department of Ophthalmology) M. Jacob, N. Suryawanshi 1987-1989
Prevention of Sole Wounds ILEP – Joint Study V.K. Pannikar, Y. Sathiyaraj, K. Jesudasan, M. Christian 1987-1989
The Study of the Role of Physiological and Immunological Factors in Human Adaptation Over Long term Exposure to Pathogenic Biopollutants Institutional Funding – In Collaboration with Clinical Research Centre, V.P. Chest Institute, Delhi M.P.S Menon, M. Christian, V.K. Pannikar, K. Jesudasan 1987-1989
Change in Prevalence of Leprosy in Gudiyattam Taluk, 1970-1985 Institutional Funding K. Jesudasan, V.K. Pannikar, M. Christian, S. Thirunavukarasu, R. Samuel, P.S.S. Rao 1987-1989
The Measurement of Electrical Impedence of Skin S. Arunthathi (Branch of Medicine)

Institutional Funding

J. Devasundaram, A. Cariappa, S. Arunthathi 1987-1989
Catract Surgery on Leprosy Patients Institutional Funding N. Suryawanshi 1987-1989
Case Detection Rates (CDR) in Gudiyattam Taluk 1962-1986 Institutional Funding – In Collaboration with Department of Biostatistics, CMC, Vellore K. Jesudasan, M. Christian, V.K. Pannikar, P. Vijayakumaran, P.S.S. Rao 1987-1989
A Study of the Physical and Social Impact of Leprosy on Patients R. Premkumar (Department of Occupational therapy and Health Education) M. V. Thomas, P. Benis, R. Premkumar 1987-1989
Neuritis in Leprosy Institutional Funding S. Arunthathi, A. Mammen, G. Helen, S. Kumar 1987-1988
Prevalence of Eye Complication among Multibacillary Leprosy Patients in Gudiyattam Taluk on WHO Multibacillary Regimen K. Jesudasan, V.K. Pannikar, and M. Christian ( Branch of Epidemiology and Leprosy Control) and M. Jacob ( Branch of Laboratories) N. Suryawanshi, K. Jesudasan, V.K. Pannikar, M. Christian, N, M. Jacob 1987-1988
Tarsal Strip Procedure for Correction of Lagopthalmus Institutional Funding N. Suryawanshi 1987
A Histopathalogical Study of Lumbrical Muscles in the Hand affected by Hansen’s Disease S. Solomon and E.P. Fritschi (Branch of Surgery) Institutional Funding J. Devasundaram, S. Solomon, E.P. Fritschi, C.J.G. Chacko 1987
Incidence Rates of Leprosy Among Household Contacts of Dapsone Resistant [DR] patients Institutional Funding K. Jesudasan, V.K. Pannikar, M. Christian, N. Manimozhi 1987 (1 year)
Evaluation of MDT as Measured by Selective Indicators Institutional Funding K. Jesudasan, M. Christian, V.K. Pannikar, R. D’ Souza 1987 (1 year)
Estimation of Rate of fall in Serum Clofazimine levels after Discontinuation of MDT Institutional Funding V.K. Pannikar, J. Balakrishnan, M. Christian 1987 (1 year)
An Electronic Device for Intermittent Auditory Cues Institutional Funding J. Devasundaram 1987 (1 year)
Adrenal Function in Leprosy Patients with Type II Lepra Reaction Jeyaraman and A.S. Kanagasabapathi (Department of Clinical Biochemistry, CMCH Vellore) Jeyaraman, S. Arunthathi, A.S. Kanagasabapathi 1987 (6 months)
Risk Factors in Social Displacement Institutional Funding M.V. Thomas, S. Sivasankaran 1987 (6 months)
Changes in Pattern of Sensory Loss in Patients Registered for Treatment Over 2 decades S. Solomon (Branch of Surgery), K. Jesudasan and M. Christian ( Branch of Epidemiology and Leprosy Control) A. Doarairaj, K. Jesudasan, S. Solomon, M. Christian 1987 (6 months)
Sensibility Testing in Early Leprosy Lesions WHO, HQ, Geneva V.K. Pannikar, M. Christian 1987 (3 months)
The Harris Mat – A Versatile Tool in the Ulcer Preventors Armamentarium R. Premkumar (Department of Occupational therapy and Health Education), J. Mc. Grindle (Department of Physiotherapy) and M. A. Hameed (Department of Orthopaedic Appliances)

Institutional Funding

S. Solomon, R. Premkumar, J. Mc. Grindle, M. A. Hameed 1987 (3 months)
Monitoring and Evaluation of Training Programs In Collaboration with S. Solomon (Branches of Medicine, Laboratories, Surgery and Epidemiology and Leprosy Control) P.Chacko, S. Arunthathi, A.Cariappa, B. Devasundaram, S. Solomon, K. Jesudasan 1987
“Care After Cure project 1: A project on Assessment and care of leprosy patients released from control in Gudiyatham Taluk” , Tamil Nadu Baptist Union of Sweden. M. Christian, K. Jesudasan, V.K. Pannikar, S. Thirunavukarasu, S. Solomon, N. Suryawanshi, M.V. Thomas 1986-1992
Profundus Minus Deformity in Leprosy S. Solomon (Branch of Surgery) R. Premkumar, S. Solomon 1986-1991
Electronic Laboratory Stirrer Institutional Funding J. Devasundaram, A. Cariappa 1986-1988
Effectieveness of the WHO Regimen in the Treatment of Paucibacillary Patients under Field Conditions Institutional Funding K. Jesudasan, M. Christian, V.K. Pannikar, P. Vijayakumaran, N. Manimozhi 1986-1988
Standardization of Skin Smears Institutional Funding B. Devasundaram, A. Cariappa, C.J.G. Chacko 1986 – 1987
Power Malfunction Alarm Institutional Funding J. Devasundaram, A. Cariappa 1986-1987
Utilization of School Teachers in the National Leprosy Eradication Programme E.P. Fritschi (Branch of Surgery) S. Sivasakaran, E.P. Fritschi 1986 (3 months)
Heterogenous Response in Reactional States of Leprosy S. Arunthathi (Branch of Medicine) A. Cariappa, S. Arunthathi, C.J.G. Chacko 1985 – 1990
Palmaris Longus Isolation and Strengthening Device Institutional Funding R. Premkumar 1985-1990
Development of an Aid to Accurately Measure Finger Oedema S. Solomon (Branch of Surgery) and Worth Industries

R. Premkumar, S.Solomon 1985-1989
Release of Proximal Inter-Phalangeal (PIP) Soft Tissue Contracture in Claw hands by Individual Finger Cylindrical Splints and whole hand Splints – A Comparative Study S. Solomon and E.P. Fritschi (Branch of Surgery) S. Joshua, A. Dorairaj, S.Solomon, E.P. Fritschi 1985-1988
Long Flexor Contractures of the Hand – An Objective Method of Assessment S. Solomon (Branch of Surgery)

Institutional Funding

N. Samuel, A. Dorairaj, S.Solomon 1985-1988
Quality Control of Skin Smears from Peripheral Leprosy Control Units K. Jesudasan ( Branch of Epidemiology and Leprosy Control) B. Devasundaram, K. Jesudasan, C.J.G. Chacko 1985-1987
A Follow-up study to compare the Palmari Longus Many Tailed and Extensor Flexor Many tailed Operations for correction of Lumbrical Paralysis S. Solomon (Branch of Surgery) A. Dorairaj, S. Solomon 1985

1984-1980

Projects Funding Agency Investigators Duration
Study of Hand Injuries following the prolonged use of Axillary Crutches Institutional Funding R. Premkumar, S. Durairaj 1984-1989
Combined Chemotherapy in Multibacillary Leprosy Institutional Funding S. Arunthathi, A. Mammen, G. Helen, S. Kumar 1984-1987
Role of Transfer Factor in the Management of Leprosy S. Arunthathi (Branch of Medicine) and J.L. Krahenbuhl and R.C. Hastings ( Gillis W. Long Hansens Disease Centre, Carville, USA) – “Indo-US Funds” C.J.G. Chacko, A. Cariappa, S. Arunthathi, J.L. Krahenbuhl, R.C. Hastings 1984-1987
Field trials of fixed duration of Combined Chemotherapy in MB leprosy World Health Organisation (WHO) 1984 – 1995
Fixed Duration Combined therapy in Multibacillary Leprosy THELEP Component of the Special Programmes for Research & Training in Tropical Diseases M. Christian, V.K. Pannikar, K. Jesudasan, P. Vijayakumaran 1984-1986
Karigiri Clofazimine and Dapsone Compliance Study Institutional Funding in collaboration with Medical research Council, London, United Kingdom G. Ellard, V.K. Pannikar, K. Jesudasan, M. Christian 1984-1987
Occult Multibacillary Leprosy C.J.G. Chacko ( Branch of Laboratories) Institutional Funding S. Arunthathi, C.J.G. Chacko, A. Mammen, G. Helen, S. Kumar 1983
Combined Chemotherapy in Paucibacillary Leprosy Institutional Funding S. Arunthathi, A. Mammen, G. Helen, S. Kumar 1983-1987
Epidemiological Impact of MDT Institutional Funding – In Collaboration with Department of Biostatistics, CMC, Vellore M. Christian, K. Jesudasan, V.K. Pannikar, P. Vijayakumaran, P.S.S. Rao, R. J. D’Souza 1982-1987
Retrospective Study of Malignancy Occuring in Chronic Plantar Ulcers Institutional Funding M. Ebenezer, S. Solomon, C.J.G. Chacko, E.P. Fritschi 1982-1987
Follow – up Study of the Effect of Epicondylectomy in Early Ulnar Neuritis Treated with Steroids Institutional Funding S. Solomon, V.K. Pannikar 1982-1987
Field Trial of combined chemotherapy (Multidrug Therapy) in MB patients World Health Organisation (WHO) M. Christian, V.K. Pannikar, K. Jesudasan 1981 – 1987
Management of Early Lateral Popliteal Neuritis Using Steroid therapy with and without long leg plaster cast – A long term follow up study V.K. Pannikar (Branch of Epidemiology and Leprosy Control) and S. Kolumban (Department of Physiotherapy)

Institutional Funding

S. Solomon, V.K. Pannikar, S. Kolumban, P. Andrews, E.P. Fritschi 1980 – 1987

1979-1968

Projects Funding Agency Investigators Duration
Correction of Foot-Drop by Tibialis Posterior Transfer: A long term follow up Institutional Funding S. Partheebarajan, S. Solomon, E.P. Fritschi 1978 – 1988
A Clinico-Pathological Study of Primary Neuritic Leprosy C.J.G. Chacko ( Branch of Laboratories) S. Arunthathi, C.J.G. Chacko, A. Mammen, G. Helen, S. Kumar 1977-1987
Domiciliary Rehabilitation Project Institutional Funding M.V. Thomas, S. Sivasankaran 1975-1987
Rehabilitation of Leprosy Patients in A Comprehensive Control Program in the Gudiyattam Taluk, S. India Swedish Red Cross – State Government of Tamil Nadu – SIHRLC

1968-1975